Radical Defense Synergy
Radical Defense Synergy
Respiratory & Immune Support | NRF2 Antioxidant Supplement Blend with Resveratrol, Quercetin, Grape Seed Extract & Pomegranate Extract | Made in Canada | 60 Vegan Capsules
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Benefits
Respiratory Support: Quercetin and nettle help modulate the body's response to environmental irritants, supporting respiratory comfort and easing immune response challenges.
Advanced Antioxidant Defense: Quercetin, resveratrol, and grape seed extract help reduce oxidative stress by activating the body's antioxidant response at the cellular level.
Clean Canadian Quality: Every Synergy Holistics product is formulated with clinically studied ingredients and produced to rigorous Canadian quality standards. Vegan, non-GMO, gluten-free, and made without artificial colours, flavours, or preservatives.
Practitioner-Formulated: Created by John Biggs, BSc., Founder of Synergy Holistics and a natural health practitioner with over 30 years of experience creating science-backed supplements trusted by thousands of Canadians.

Ultimate Antioxidant and Anti-Inflammatory Support
Experience the power of Radical Defense Synergy, a potent blend of botanicals designed to provide exceptional antioxidant and anti-inflammatory benefits. This advanced formula features Resveratrol, Quercetin, Nettle root, Grapeseed Extract, Pomegranate, and Acai, which work together to combat free radicals and reduce inflammation. Ideal for allergy sufferers and those seeking to combat "inflammaging," Radical Defense Synergy activates the Nrf2 pathway, enhancing your body’s natural defenses. With proven ingredients that help decrease histamine release and boost immune health, this supplement is your go-to for maintaining a balanced, healthy lifestyle year-round.
Facts & Usage
Recommended Use: Source of antioxidants for the maintenance of good health; helps support healthy aging.
Recommended Dose: 1 capsule twice daily. Take with food.
| Serving Size: 1 Capsule | ||
| Servings Per Container: 60 | ||
| Per Serving | ||
| Trans-Resveratrol | 50 mg | |
| Nettle (Urtica dioica) leaf | 125 mg | |
| Quercetin (3,3',4',5,7-Pentahydroxyflavone) | 100 mg | |
| Pomegranate (Punica granatum) (40% Ellagic acid) | 50 mg | |
| Acai (Euterpe oleracea) | 100 mg | |
| Grape Seed Extract (Vitis Vinifera) (40:1 90% Polyphenols) | 25 mg | |
| Non-Medicinal Ingredients: Vegetarian capsule (hypromellose), microcrystalline cellulose, magnesium stearate (veg), silicon dioxide. | ||
| Contains NO artificial colours, flavours, preservatives, wheat, gluten, corn, yeast, dairy, or soy. | ||
The Synergy Holistics Radical Defense Synergy is well-balanced, plant-based, and easy to use. It comes in a sealed bottle with 60 vegetarian capsules, and the label clearly outlines the key ingredients, including resveratrol, quercetin, grape seed extract, and pomegranate.The capsules are smooth and easy to swallow with no aftertaste. The dosage is simple, just two capsules a day, and there are no artificial additives or fillers listed. This supplement is designed to support the body’s natural antioxidant response. These ingredients are commonly used for their antioxidant properties and are often included in routines aimed at immune and respiratory support. Overall, it’s a clean, Canadian-made antioxidant blend that fits well into a daily wellness routine. Full marks from me!
It is not possible to objectively evaluate the benefits or the efficacy of supplements through ordinary home use; so, I will not get into this product's effectiveness, and you can search the Internet for the benefits of the main ingredients of this product.It is clearly indicated on the bottle that it was manufactured in Canada, and it has an NPN number (Natural Product Number) that can be used to confirm that it was licensed in March 2014, and the license was revised in October 2024. There are 5 brand names associated with the license, and the license holder is Optimum Health Vitamins & More.Similar to the label on the product, the NPN product information page lists 6 medicinal ingredients. Risk information on the NPN page is as follows:"Cautions and WarningsIf you are taking prescription medication, consult a healthcare practitioner prior to use as resveratrol may alter the effectiveness of these medication.Contra-IndicationsDo not use if you are pregnant or breastfeeding.Known Adverse ReactionsHypersensitivity/allergy has been known to occur to acai or plants of the Arecaeae family. In such a case, discontinue use."It comes in a container with 60 capsules in it. The recommended dosage is 1 capsule, twice daily, with food, which should have the bottle last for a month if you follow the recommended dosage. The price was $30 CAD at the time of writing.While I cannot confirm the claimed benefits or the product's efficacy, I see no reason to cut any stars from my rating. I appreciate that it was made in Canada and that it comes with a proper NPN number on the bottle.
I’m happy to try out Radical Defense Synergy. I like that it is a combination of resveratrol, quercetin and grape seed extract. These are known to have anti-oxidant and anti-inflammatory benefits.This is a quality product made in Canada. Price is fair for one-month supply. Just one small thing - dosage is 2 per day but perhaps 1 per day would be easier especially when it's necessary to take other supplements or medicine on a daily basis.Things I like:- Product of Canada.- NPN number to indicate the product has been authorized for sale in Canada.- Triple tested. GMP-certified.- Non-GMO, dairy free, gluten free, soy free. No artificial colors, flavors, or preservatives.- Bottle is properly protection sealed.- Long expiration date Mar 2027.
I am taking these capsules for health support, this winter I got hit with a few seasonal respiratory illnesses and I feel better taking these.The supplement is a combo of various extracts, such as resveratrol, nettle, pomegranate , grape seed and other, most of which I have taken separately in the past. As expected I had no ill side effects, I enjoy taking them to improve my immune function.I really like the concept and the realization of this supplement, the fact that it is Canadian made and it has all certificates and NPN in order.The labels are hard to read, now it’s true that a lot of information is printed on a very small space.I like thisThank you
I would give this 4.5 stars if possible. Great product from a great company. I find the entire line from Synergy Holistics very beneficial and powerful. Its seems to come at a bit of a premium price however. I don't see any mention of 3rd party testing which is unfortunate. Between that and the premium price I can't give it a full 5 stars.